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2019 EFFECT OF SCAFFOLD DESIGN ON MECHANICAL PROPERTIES IN BONE

Scaffolds are structural components developed to repair / restore damaged tissue and organs in bone tissue engineering. The architecture of the porous scaffolds used for bone tissue engineering has recently been shown to significantly affect cellular response and bone tissue regeneration rate. One of the most important factors to consider when designing scaffolds is what organ or tissue to use. This should be done by considering the scaffold design. Pore size and porosity are different characteristics and directly affect interconnectivity, which is the most important parameter for cell development and proliferation. However, due to the fact that bone tissues carry the load, their mechanical properties must also provide this requirement. Therefore, the most fundamental problem that needs to come from bone tissue engineering is to provide the necessary mechanical properties when designing the optimum scaffold architecture. Scaffold architecture, pore structure and size, surface area, strength of mechanical properties, cell seeding and growth, and biodegradation speed are the main factors that make scaffold design and production complex and difficult to implement. 3D printers have greatly simplified this challenge by simplifying the application of more precise designs than traditional methods. In this review, we emphasize the recent developments in bone scaffolds and still need to be improved.

International Congress on 3D Printing (Additive Manufacturing) Technologies and Digital Industry
3D-PTC2019

Zeynep EKSI Aleyna KUCUKAY Didem OZCIMEN Cem Bülent Üstündağ

228 384
Subject Area: Engineering Broadcast Area: International Type: Article Language: English