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Scaffolds are structural components developed to repair / restore damaged tissue and organs in bone
tissue engineering. The architecture of the porous scaffolds used for bone tissue engineering has
recently been shown to significantly affect cellular response and bone tissue regeneration rate. One of
the most important factors to consider when designing scaffolds is what organ or tissue to use. This
should be done by considering the scaffold design. Pore size and porosity are different characteristics
and directly affect interconnectivity, which is the most important parameter for cell development and
proliferation. However, due to the fact that bone tissues carry the load, their mechanical properties
must also provide this requirement. Therefore, the most fundamental problem that needs to come from
bone tissue engineering is to provide the necessary mechanical properties when designing the
optimum scaffold architecture. Scaffold architecture, pore structure and size, surface area, strength of
mechanical properties, cell seeding and growth, and biodegradation speed are the main factors that
make scaffold design and production complex and difficult to implement. 3D printers have greatly
simplified this challenge by simplifying the application of more precise designs than traditional
methods. In this review, we emphasize the recent developments in bone scaffolds and still need to be
improved.
International Congress on 3D Printing (Additive Manufacturing) Technologies and Digital Industry
3D-PTC2019
Zeynep EKSI
Aleyna KUCUKAY
Didem OZCIMEN
Cem Bülent Üstündağ